| 000 | nam a22 7a 4500 | ||
|---|---|---|---|
| 999 |
_c6134 _d6134 |
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| 008 | 220509b xxu||||| |||| 00| 0 vie d | ||
| 020 |
_a9783319618036 _c2053900 |
||
| 082 | 0 | 4 |
_223rd ed. _a579.2 _bH945 |
| 100 | 1 | _aHunter, Eric | |
| 245 | 1 | 0 |
_aViruses, genes, and cancer _cEric Hunter, Klaus Bister |
| 260 |
_aSwitzerland _bSpringer _c2017 |
||
| 300 |
_axiii, 221 p. _bill. _c24cm |
||
| 490 | 0 | _aCurrent topics in Microbiology and immunology | |
| 520 | 3 | _aThis volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. | |
| 653 | _aY đa khoa | ||
| 700 | 1 | _aBister, Klaus | |
| 942 |
_2ddc _cBK |
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