Viruses, genes, and cancer Eric Hunter, Klaus Bister
Tác giả: Hunter, Eric.
Contributor(s): Bister, Klaus.
Tùng thư: Current topics in Microbiology and immunology.Nhà xuất bản: Switzerland Springer 2017Thông tin mô tả: xiii, 221 p. ill. 24cm.Số ISBN: 9783319618036.Chủ đề: Y đa khoaSố phân loại DDC: 579.2 Tóm tắt: This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment.| Kiểu tài liệu | Thư viện hiện tại | Ký hiệu phân loại | Trạng thái | Ngày hết hạn | Đăng ký cá biệt |
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Sách
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579.2 H945 (Xem kệ sách) | Sẵn sàng | MD.19415 |
This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment.
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